Anti-TPO Antibody

In autoimmune thyroid disorders, such as Hashimoto`s thyroiditis and Graves’ disease, the immune system produces antibodies against thyroid peroxidase (TPO), an enzyme found in the thyroid gland. An Anti-TPO Antibody(Anti-Thyroid Peroxidase Antibody) test detects and measures the levels of these anti-thyroid peroxidase (anti-TPO) antibodies in your blood.

TPO is found in the cells of the thyroid follicle and helps produce the thyroid hormones thyroxine (T4) or triiodothyronine (T3). The presence of anti-TPO antibodies indicates autoimmune activity against the thyroid gland. These antibodies contribute to inflammation and damage to thyroid cells, thus leading to thyroid dysfunction.